Roles of partly unfolded conformations in macromolecular self-assembly

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Macromolecular self-assembly and nanotechnology in China.

Macromolecular self-assembly refers to the assembly of synthetic polymers, biomacromolecules and supra-molecular polymers. Through macromolecular self-assembly, the fabrication of ordered structures at different scales, the control of the dynamic assembly process and the integrations of advanced functions can be realized. Macromolecular self-assembly and nanotechnology research in China has dev...

متن کامل

Stitchprofiles.uio.no: analysis of partly melted DNA conformations using stitch profiles

In this study, we describe a web server that performs computations on DNA melting, thus predicting the localized separation of the two strands for sequences provided by the users. The output types are stitch profiles, melting curves, probability profiles, etc. Stitch profile diagrams visualize the ensemble of alternative conformations that DNA can adopt with different probabilities. For example...

متن کامل

An automatic tool to analyze and cluster macromolecular conformations based on self-organizing maps

MOTIVATION Sampling the conformational space of biological macromolecules generates large sets of data with considerable complexity. Data-mining techniques, such as clustering, can extract meaningful information. Among them, the self-organizing maps (SOMs) algorithm has shown great promise; in particular since its computation time rises only linearly with the size of the data set. Whereas SOMs ...

متن کامل

Refinement of protein conformations using a macromolecular energy minimization procedure.

This paper presents a rapid refinement procedure capable of deriving the stable conformation of a macromolecule from experimental model co-ordinates. All the degrees of freedom of the molecule are allowed to vary and all parts of the structure are refined simultaneously in a general force-field. The procedure has been applied to myoglobin and lysozyme. The deviations of peptide bonds from plana...

متن کامل

Nucleating the assembly of macromolecular complexes.

Nature constructs intricate complexes containing numerous binding partners in order to direct a variety of cellular processes. Researchers have taken a cue from these events to develop synthetic molecules that can nucleate natural and unnatural interactions for a diverse set of applications. These molecules can be designed to drive protein dimerization or to modulate the interactions between pr...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Genes to Cells

سال: 2001

ISSN: 1356-9597

DOI: 10.1046/j.1365-2443.2001.00384.x